About In-vitro In-vivo In-silico Journal
A multidisciplinary platform bridging experimental biology, computational modeling, and translational research across the life sciences
Advancing Integrative Research Methodologies
In-vitro In-vivo In-silico Journal (IIIJ) is a pioneering multidisciplinary journal dedicated to publishing high-quality research that employs diverse experimental and computational approaches in the life sciences. Our journal serves as a nexus for researchers utilizing in-vitro (laboratory/cell-based), in-vivo (organism-based), and in-silico (computational modeling) methodologies to address fundamental and applied questions in biology, medicine, pharmacology, and related fields.
IIIJ embraces interdisciplinary scholarship that advances our understanding of biological systems through complementary research strategies. We publish original research, comprehensive reviews, methodological innovations, and case studies that demonstrate the synergy between experimental validation and computational prediction.
Understanding the Three Research Paradigms
The journal's title reflects the three fundamental approaches that drive modern biological research:
Latin for "in glass" - experiments conducted in controlled laboratory environments using cells, tissues, or biomolecules outside their natural biological context, enabling precise manipulation and observation.
Latin for "in the living" - studies performed within whole, living organisms, providing insights into complex biological interactions, physiological responses, and system-level phenomena.
Modern Latin for "in silicon" (computer chips) - computational and mathematical modeling approaches that simulate biological processes, predict outcomes, and guide experimental design.
IIIJ welcomes submissions across a broad spectrum of life sciences disciplines, embracing research that employs any combination of in-vitro, in-vivo, and in-silico methodologies. Our interdisciplinary scope includes but is not limited to:
Molecular and Cellular Biology
- Cell signaling and gene regulation
- Protein structure and function
- Cellular metabolism and energetics
- Cell culture methodologies
Pharmacology and Drug Development
- Drug screening and validation
- Pharmacokinetics and pharmacodynamics
- Toxicology and safety assessment
- Target identification and validation
Computational Biology and Bioinformatics
- Molecular modeling and simulation
- Systems biology approaches
- Genomic and proteomic analysis
- Network biology and pathway analysis
Biomedicine and Translational Research
- Disease modeling and mechanisms
- Biomarker discovery and validation
- Regenerative medicine
- Personalized medicine approaches
Biochemistry and Structural Biology
- Enzyme kinetics and mechanisms
- Protein-ligand interactions
- Structural prediction and analysis
- Metabolic pathway engineering
Physiology and Experimental Medicine
- Organ system function and regulation
- Disease pathophysiology
- Animal models of human disease
- Comparative physiology
For detailed information about acceptable topics and research areas, please consult our comprehensive Aim and Scope page.
Types of Submissions We Welcome
IIIJ maintains rigorous standards for scientific quality, ethical conduct, and manuscript preparation. All submissions undergo thorough peer review by experts in relevant fields. Authors must adhere to the following requirements:
Manuscript Preparation: All submissions must follow our detailed Instructions for Authors, which specify formatting requirements, citation styles, figure preparation, supplementary material guidelines, and data availability policies.
- Manuscripts must be written in clear, professional English with proper scientific terminology
- All work must be original and not under consideration elsewhere
- Proper attribution and citation of previous work is mandatory
- Ethical approval documentation for animal or human studies must be provided
- Conflicts of interest and funding sources must be disclosed
- Data availability statements are required for reproducibility
- Rigorous yet constructive peer review process ensuring scientific quality while supporting author development
- Rapid editorial decisions and efficient production timelines minimizing time to publication
- Open access model ensuring maximum visibility and impact for your research
- Broad multidisciplinary readership spanning experimental and computational life sciences
- Permanent digital archiving and DOI assignment for long-term accessibility
- Comprehensive indexing in major academic databases increasing discoverability
- Flexible article formats accommodating diverse research communication needs
- Professional production support including language editing services
Article Processing Charges: As an open access journal, IIIJ charges article processing fees upon acceptance to cover peer review coordination, production, hosting, indexing, and dissemination costs. Detailed information about fees and available waivers can be found on our Article Processing Charges page.
IIIJ is guided by a distinguished international Editorial Board comprising leading researchers, clinicians, and computational scientists from diverse disciplines. Our editors bring expertise across molecular biology, pharmacology, computational modeling, systems biology, and translational medicine, ensuring comprehensive and authoritative peer review.
The editorial team is committed to maintaining the highest standards of scientific integrity, promoting interdisciplinary collaboration, and advancing responsible research practices across all methodological approaches.
Submit Your Research to IIIJ
Join a global community of researchers advancing the life sciences through innovative in-vitro, in-vivo, and in-silico methodologies. Share your findings with a multidisciplinary audience committed to rigorous, reproducible, and impactful science.
Questions or Need Assistance? Contact our editorial office at [email protected]
